The feasibility of myocardial infarct visualization using atrial kick induced strain (AKIS) contrast.

Journal Article (Journal Article)

The most common mechanical measure of the heart integrates ventricular strain between end-diastole and end-systole in order to provide a measure of contraction. Here an approach is described for estimating a correlate to local passive mechanical properties. Passive strain is measured by estimating ventricular strain during atrial systole. During atrial systole the atria contract causing passive stretching in the ventricles from increased volume. This modification to traditional cardiac strain is here termed atrial kick induced strain (AKIS) imaging. AKIS imaging was evaluated in a canine ablation model of chronic infarct and a canine true chronic infarct model. AKIS images of ablation lesions were compared against acoustic radiation force impulse (ARFI) images and tissue blanching, and true chronic infarct AKIS images were compared against delayed enhanced-contrast magnetic resonance. AKIS images were made with 2-D and 3-D ultrasound data. In both studies, AKIS images and the comparison images show good qualitative agreement and good contrast and contrast-to-noise ratio.

Full Text

Duke Authors

Cited Authors

  • Byram, B; Kim, H; Van Assche, L; Wolf, PD; Trahey, GE

Published Date

  • June 2014

Published In

Volume / Issue

  • 40 / 6

Start / End Page

  • 1104 - 1117

PubMed ID

  • 24613554

Pubmed Central ID

  • PMC4096930

Electronic International Standard Serial Number (EISSN)

  • 1879-291X

Digital Object Identifier (DOI)

  • 10.1016/j.ultrasmedbio.2013.12.022


  • eng

Conference Location

  • England