A32: Low Vitamin D Status is Associated with Avascular Necrosis: An Atherosclerosis Prevention in Pediatric Lupus Erythematosus Substudy.

Journal Article

Avascular necrosis (AVN) can result in significant morbidity. Previous studies suggest that AVN is associated with systemic lupus erythematosus (SLE) and corticosteroid treatment. Hypovitaminosis D has been postulated to play a role in bisphosphonate-associated osteonecrosis of the jaw. Using frozen serum and demographic data from the Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) trial, we conducted an exploratory analysis to assess associations between AVN and demographics, SLE disease activity and vitamin D deficiency, defined as serum 25-hydroxyvitamin D [25(OH)D] <20 ng/mL.

Full Text

Duke Authors

Cited Authors

  • Gurion, R; Tangpricha, V; Yow, E; Schanberg, LE; McComsey, G; Robinson, A; APPLE Investigators,

Published Date

  • March 2014

Published In

Volume / Issue

  • 66 Suppl 11 /

Start / End Page

  • S49 - S50

PubMed ID

  • 24677960

Pubmed Central ID

  • 24677960

Electronic International Standard Serial Number (EISSN)

  • 2326-5205

Digital Object Identifier (DOI)

  • 10.1002/art.38448


  • eng

Conference Location

  • United States