Transcriptomic analysis of the highly derived radial body plan of a sea urchin.

Published

Journal Article (Letter)

With their complex life cycle and highly derived body plan, echinoderms are unique among bilaterians. Although early development has been intensively studied, the molecular mechanisms underlying development of the adult echinoderm and its unusual radial body plan are largely unknown. To investigate the evolution of developmental changes in gene expression underlying radial body plan development and metamorphosis, we assembled a reference transcriptome de novo and used RNA-seq to measure gene expression profiles across larval, metamorphic, and postmetamorphic life cycle phases in the sea urchin Heliocidaris erythrogramma. Our results present a high-resolution view of gene expression dynamics during the complex transition from pre- to postmetamorphic development and suggest that distinct sets of regulatory and effector proteins are used during different life history phases. These analyses provide an important foundation for more detailed analyses of the evolution of the radial adult body of echinoderms.

Full Text

Duke Authors

Cited Authors

  • Wygoda, JA; Yang, Y; Byrne, M; Wray, GA

Published Date

  • April 2014

Published In

Volume / Issue

  • 6 / 4

Start / End Page

  • 964 - 973

PubMed ID

  • 24696402

Pubmed Central ID

  • 24696402

Electronic International Standard Serial Number (EISSN)

  • 1759-6653

International Standard Serial Number (ISSN)

  • 1759-6653

Digital Object Identifier (DOI)

  • 10.1093/gbe/evu070

Language

  • eng