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Transcriptomic analysis of the highly derived radial body plan of a sea urchin.

Publication ,  Journal Article
Wygoda, JA; Yang, Y; Byrne, M; Wray, GA
Published in: Genome biology and evolution
April 2014

With their complex life cycle and highly derived body plan, echinoderms are unique among bilaterians. Although early development has been intensively studied, the molecular mechanisms underlying development of the adult echinoderm and its unusual radial body plan are largely unknown. To investigate the evolution of developmental changes in gene expression underlying radial body plan development and metamorphosis, we assembled a reference transcriptome de novo and used RNA-seq to measure gene expression profiles across larval, metamorphic, and postmetamorphic life cycle phases in the sea urchin Heliocidaris erythrogramma. Our results present a high-resolution view of gene expression dynamics during the complex transition from pre- to postmetamorphic development and suggest that distinct sets of regulatory and effector proteins are used during different life history phases. These analyses provide an important foundation for more detailed analyses of the evolution of the radial adult body of echinoderms.

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Published In

Genome biology and evolution

DOI

EISSN

1759-6653

ISSN

1759-6653

Publication Date

April 2014

Volume

6

Issue

4

Start / End Page

964 / 973

Related Subject Headings

  • Transcriptome
  • Sea Urchins
  • Metamorphosis, Biological
  • Gene Expression Regulation, Developmental
  • Developmental Biology
  • Body Patterning
  • Animals
  • 3105 Genetics
  • 3104 Evolutionary biology
  • 3101 Biochemistry and cell biology
 

Citation

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Wygoda, J. A., Yang, Y., Byrne, M., & Wray, G. A. (2014). Transcriptomic analysis of the highly derived radial body plan of a sea urchin. Genome Biology and Evolution, 6(4), 964–973. https://doi.org/10.1093/gbe/evu070
Wygoda, Jennifer A., Yee Yang, Maria Byrne, and Gregory A. Wray. “Transcriptomic analysis of the highly derived radial body plan of a sea urchin.Genome Biology and Evolution 6, no. 4 (April 2014): 964–73. https://doi.org/10.1093/gbe/evu070.
Wygoda JA, Yang Y, Byrne M, Wray GA. Transcriptomic analysis of the highly derived radial body plan of a sea urchin. Genome biology and evolution. 2014 Apr;6(4):964–73.
Wygoda, Jennifer A., et al. “Transcriptomic analysis of the highly derived radial body plan of a sea urchin.Genome Biology and Evolution, vol. 6, no. 4, Apr. 2014, pp. 964–73. Epmc, doi:10.1093/gbe/evu070.
Wygoda JA, Yang Y, Byrne M, Wray GA. Transcriptomic analysis of the highly derived radial body plan of a sea urchin. Genome biology and evolution. 2014 Apr;6(4):964–973.
Journal cover image

Published In

Genome biology and evolution

DOI

EISSN

1759-6653

ISSN

1759-6653

Publication Date

April 2014

Volume

6

Issue

4

Start / End Page

964 / 973

Related Subject Headings

  • Transcriptome
  • Sea Urchins
  • Metamorphosis, Biological
  • Gene Expression Regulation, Developmental
  • Developmental Biology
  • Body Patterning
  • Animals
  • 3105 Genetics
  • 3104 Evolutionary biology
  • 3101 Biochemistry and cell biology