Arsenic exposure of rural populations from the Rift Valley of Ethiopia as monitored by keratin in toenails

Published

Journal Article

Arsenic (As) contamination of drinking water is a worldwide phenomenon whose effect among vulnerable and rural communities in the Rift Valley of Ethiopia in eastern Africa is not well studied. This study examines As exposure and bioaccumulation from drinking water by monitoring human keratin in the form of toenails from exposed populations. Groundwater samples from drinking water wells (n=34) were collected along with toenail samples (n=58) from local communities and were analyzed for trace metals including As by inductively coupled plasma mass spectrometry (ICP-MS). Of the total number of wells tested, 53% had As level above the WHO maximum contamination level of 10 p.p.b. Arsenic in toenails was significantly correlated to corresponding drinking water (r=0.72; R 2 =0.52; P<0.001). This correlation improves for drinking water with As concentrations above 2 p.p.b. (r=0.74; R 2 =0.54; P<0.001). Male minors (<18 years old) were found to have greater nail-As concentrations compared with adults consuming equal amounts of As (P<0.05). Estimated As dose specifically from drinking water sources was also associated with nail concentrations (P<0.01). We suggest that As measurement in nails could be a reliable method for detecting As exposure in residents living in rural areas. © 2014 Nature America, Inc.

Full Text

Duke Authors

Cited Authors

  • Merola, RB; Kravchenko, J; Rango, T; Vengosh, A

Published Date

  • March 1, 2014

Published In

Volume / Issue

  • 24 / 2

Start / End Page

  • 121 - 126

Electronic International Standard Serial Number (EISSN)

  • 1559-064X

International Standard Serial Number (ISSN)

  • 1559-0631

Digital Object Identifier (DOI)

  • 10.1038/jes.2013.77

Citation Source

  • Scopus