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Weight loss and metabolic benefits with diets of varying fat and carbohydrate content: separating the wheat from the chaff.

Publication ,  Journal Article
Brehm, BJ; D'Alessio, DA
Published in: Nat Clin Pract Endocrinol Metab
March 2008

With the rising prevalence of both obesity and diabetes, the contributing role of diet to the prevention and treatment of these conditions has become a major focus of research, clinical practice, and public policy. There has been intense debate over which dietary regimens might be most effective for weight loss, with interest centered on the potential for specific dietary macronutrients to affect body composition, metabolism, and overall health. This Review addresses two regimens with distinct macronutrient prescriptions that have been widely touted as being beneficial for weight loss and/or metabolic profile: diets low in carbohydrate and diets high in monounsaturated fat. Although data from recent randomized, controlled trials suggest these popular diets may be useful for weight control, cardiovascular health, and glycemic control, longer studies of the efficacy and safety of varying macronutrient content are needed to strengthen the evidence base for nutritional recommendations. Until more support for specific macronutrient combinations is available, practitioners can recommend an array of diets with moderate amounts of macronutrients, tailored to individual needs and preferences.

Duke Scholars

Published In

Nat Clin Pract Endocrinol Metab

DOI

EISSN

1745-8374

Publication Date

March 2008

Volume

4

Issue

3

Start / End Page

140 / 146

Location

England

Related Subject Headings

  • Weight Loss
  • Humans
  • Endocrinology & Metabolism
  • Dietary Fats
  • Dietary Carbohydrates
  • Diet, Fat-Restricted
  • Diet, Carbohydrate-Restricted
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Brehm, B. J., & D’Alessio, D. A. (2008). Weight loss and metabolic benefits with diets of varying fat and carbohydrate content: separating the wheat from the chaff. Nat Clin Pract Endocrinol Metab, 4(3), 140–146. https://doi.org/10.1038/ncpendmet0730
Brehm, Bonnie J., and David A. D’Alessio. “Weight loss and metabolic benefits with diets of varying fat and carbohydrate content: separating the wheat from the chaff.Nat Clin Pract Endocrinol Metab 4, no. 3 (March 2008): 140–46. https://doi.org/10.1038/ncpendmet0730.
Brehm BJ, D’Alessio DA. Weight loss and metabolic benefits with diets of varying fat and carbohydrate content: separating the wheat from the chaff. Nat Clin Pract Endocrinol Metab. 2008 Mar;4(3):140–6.
Brehm, Bonnie J., and David A. D’Alessio. “Weight loss and metabolic benefits with diets of varying fat and carbohydrate content: separating the wheat from the chaff.Nat Clin Pract Endocrinol Metab, vol. 4, no. 3, Mar. 2008, pp. 140–46. Pubmed, doi:10.1038/ncpendmet0730.
Brehm BJ, D’Alessio DA. Weight loss and metabolic benefits with diets of varying fat and carbohydrate content: separating the wheat from the chaff. Nat Clin Pract Endocrinol Metab. 2008 Mar;4(3):140–146.

Published In

Nat Clin Pract Endocrinol Metab

DOI

EISSN

1745-8374

Publication Date

March 2008

Volume

4

Issue

3

Start / End Page

140 / 146

Location

England

Related Subject Headings

  • Weight Loss
  • Humans
  • Endocrinology & Metabolism
  • Dietary Fats
  • Dietary Carbohydrates
  • Diet, Fat-Restricted
  • Diet, Carbohydrate-Restricted
  • 1103 Clinical Sciences