Thermic effect of food in lean and obese men.


Journal Article

A systemic reappraisal of the thermic effect of food was done in lean and obese males randomly fed mixed meals containing 0, 8, 16, 24, and 32 kcal/kg fat-free mass. Densitometric analysis was used to measure body composition. Preprandial and postprandial energy expenditures were measured by indirect calorimetry. The data show that the thermic effect of food was linearly correlated with caloric intake, and that the magnitude and duration of augmented postprandial thermogenesis increased linearly with caloric consumption. Postprandial energy expenditures over resting metabolic requirements were indistinguishable when comparing lean and obese men for a given caloric intake. Individuals, however, had distinct and consistent thermic responses to progressively greater caloric challenges. These unique thermic profiles to food ingestion were also independent of leanness or obesity. We conclude that the thermic effect of food increases linearly with caloric intake, and is independent of leanness and obesity.

Full Text

Duke Authors

Cited Authors

  • D'Alessio, DA; Kavle, EC; Mozzoli, MA; Smalley, KJ; Polansky, M; Kendrick, ZV; Owen, LR; Bushman, MC; Boden, G; Owen, OE

Published Date

  • June 1988

Published In

Volume / Issue

  • 81 / 6

Start / End Page

  • 1781 - 1789

PubMed ID

  • 3384951

Pubmed Central ID

  • 3384951

International Standard Serial Number (ISSN)

  • 0021-9738

Digital Object Identifier (DOI)

  • 10.1172/JCI113520


  • eng

Conference Location

  • United States