Global cardiovascular research output, citations, and collaborations: a time-trend, bibliometric analysis (1999-2008).

Journal Article (Journal Article)

INTRODUCTION: Health research is one mechanism to improve population-level health and should generally match the health needs of populations. However, there have been limited data to assess the trends in national-level cardiovascular research output, even as cardiovascular disease [CVD] has become the leading cause of morbidity and mortality worldwide. MATERIALS AND METHODS: We performed a time trends analysis of cardiovascular research publications (1999-2008) downloaded from Web of Knowledge using a iteratively-tested cardiovascular bibliometric filter with >90% precision and recall. We evaluated cardiovascular research publications, five-year running actual citation indices [ACIs], and degree of international collaboration measured through the ratio of the fractional count of addresses from one country against all addresses for each publication. RESULTS AND DISCUSSION: Global cardiovascular publication volume increased from 40 661 publications in 1999 to 55 284 publications in 2008, which represents a 36% increase. The proportion of cardiovascular publications from high-income, Organization for Economic Cooperation and Development [OECD] countries declined from 93% to 84% of the total share over the study period. High-income, OECD countries generally had higher fractional counts, which suggest less international collaboration, than lower income countries from 1999-2008. There was an inverse relationship between cardiovascular publications and age-standardized CVD morbidity and mortality rates, but a direct, curvilinear relationship between cardiovascular publications and Human Development Index from 1999-2008. CONCLUSIONS: Cardiovascular health research output has increased substantially in the past decade, with a greater share of citations being published from low- and middle-income countries. However, low- and middle-income countries with the higher burdens of cardiovascular disease continue to have lower research output than high-income countries, and thus require targeted research investments to improve cardiovascular health.

Full Text

Duke Authors

Cited Authors

  • Huffman, MD; Baldridge, A; Bloomfield, GS; Colantonio, LD; Prabhakaran, P; Ajay, VS; Suh, S; Lewison, G; Prabhakaran, D

Published Date

  • 2013

Published In

Volume / Issue

  • 8 / 12

Start / End Page

  • e83440 -

PubMed ID

  • 24391769

Pubmed Central ID

  • PMC3877050

Electronic International Standard Serial Number (EISSN)

  • 1932-6203

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0083440


  • eng

Conference Location

  • United States