Breast cancer version 3.2014.

Journal Article (Journal Article)

Breast cancer is the most common malignancy in women in the United States and is second only to lung cancer as a cause of cancer death. The overall management of breast cancer includes the treatment of local disease with surgery, radiation therapy, or both, and the treatment of systemic disease with cytotoxic chemotherapy, endocrine therapy, biologic therapy, or combinations of these. The NCCN Guidelines specific to management of large clinical stage II and III tumors are discussed in this article. These guidelines are the work of the members of the NCCN Breast Cancer Panel. Expert medical clinical judgment is required to apply these guidelines in the context of an individual patient to provide optimal care. Although not stated at every decision point of the guidelines, patient participation in prospective clinical trials is the preferred option of treatment for all stages of breast cancer.

Full Text

Duke Authors

Cited Authors

  • Gradishar, WJ; Anderson, BO; Blair, SL; Burstein, HJ; Cyr, A; Elias, AD; Farrar, WB; Forero, A; Giordano, SH; Goldstein, LJ; Hayes, DF; Hudis, CA; Isakoff, SJ; Ljung, B-ME; Marcom, PK; Mayer, IA; McCormick, B; Miller, RS; Pegram, M; Pierce, LJ; Reed, EC; Salerno, KE; Schwartzberg, LS; Smith, ML; Soliman, H; Somlo, G; Ward, JH; Wolff, AC; Zellars, R; Shead, DA; Kumar, R; National Comprehensive Cancer Network Breast Cancer Panel,

Published Date

  • April 2014

Published In

Volume / Issue

  • 12 / 4

Start / End Page

  • 542 - 590

PubMed ID

  • 24717572

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2014.0058


  • eng

Conference Location

  • United States