[Bradykinin modulates ion channel in inflammatory pain].


Journal Article (Review)

Injury or inflammation induces release of a range of inflammatory mediators. Bradykinin is one of the most important inflammatory mediators and plays a crucial role in mediating inflammatory pain. It is well known that multiple ion channels located in the nociceptors participate in pain sensation. Recent studies demonstrate an important role of bradykinin in regulating the function and expression of pain-related ion channels. This paper summarizes the recent advances in the understanding of the role of bradykinin in modulation of the channels and discusses future possibilities in the treatment of inflammatory pain.

Full Text

Duke Authors

Cited Authors

  • Liu, B-Y; Zhang, H-L

Published Date

  • October 2009

Published In

Volume / Issue

  • 44 / 10

Start / End Page

  • 1066 - 1071

PubMed ID

  • 20055126

Pubmed Central ID

  • 20055126

International Standard Serial Number (ISSN)

  • 0513-4870


  • chi

Conference Location

  • China