Tumor acquisition for biomarker research in lung cancer.

Journal Article (Journal Article)

The biopsy collection data from two lung cancer trials that required fresh tumor samples be obtained for microarray analysis were reviewed. In the trial for advanced disease, microarray data were obtained on 50 patient samples, giving an overall success rate of 60.2%. The majority of the specimens were obtained through CT-guided lung biopsies (N = 30). In the trial for early-stage patients, 28 tissue specimens were collected from excess tumor after surgical resection with a success rate of 85.7%. This tissue procurement program documents the feasibility in obtaining fresh tumor specimens prospectively that could be used for molecular testing.

Full Text

Duke Authors

Cited Authors

  • Stevenson, M; Christensen, J; Shoemaker, D; Foster, T; Barry, WT; Tong, BC; Wahidi, M; Shofer, S; Datto, M; Ginsburg, G; Crawford, J; D'Amico, T; Ready, N

Published Date

  • July 2014

Published In

Volume / Issue

  • 32 / 6

Start / End Page

  • 291 - 298

PubMed ID

  • 24810245

Pubmed Central ID

  • PMC4336177

Electronic International Standard Serial Number (EISSN)

  • 1532-4192

Digital Object Identifier (DOI)

  • 10.3109/07357907.2014.911880


  • eng

Conference Location

  • England