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Principles of T2 *-weighted dynamic susceptibility contrast MRI technique in brain tumor imaging.

Publication ,  Journal Article
Shiroishi, MS; Castellazzi, G; Boxerman, JL; D'Amore, F; Essig, M; Nguyen, TB; Provenzale, JM; Enterline, DS; Anzalone, N; Dörfler, A; Law, M ...
Published in: J Magn Reson Imaging
February 2015

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is used to track the first pass of an exogenous, paramagnetic, nondiffusible contrast agent through brain tissue, and has emerged as a powerful tool in the characterization of brain tumor hemodynamics. DSC-MRI parameters can be helpful in many aspects, including tumor grading, prediction of treatment response, likelihood of malignant transformation, discrimination between tumor recurrence and radiation necrosis, and differentiation between true early progression and pseudoprogression. This review aims to provide a conceptual overview of the underlying principles of DSC-MRI of the brain for clinical neuroradiologists, scientists, or students wishing to improve their understanding of the technical aspects, pitfalls, and controversies of DSC perfusion MRI of the brain. Future consensus on image acquisition parameters and postprocessing of DSC-MRI will most likely allow this technique to be evaluated and used in high-quality multicenter studies and ultimately help guide clinical care.

Duke Scholars

Published In

J Magn Reson Imaging

DOI

EISSN

1522-2586

Publication Date

February 2015

Volume

41

Issue

2

Start / End Page

296 / 313

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Neoplasm Recurrence, Local
  • Neoplasm Grading
  • Magnetic Resonance Imaging
  • Humans
  • Hemodynamics
  • Disease Progression
  • Contrast Media
  • Brain Neoplasms
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
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Shiroishi, M. S., Castellazzi, G., Boxerman, J. L., D’Amore, F., Essig, M., Nguyen, T. B., … Law, M. (2015). Principles of T2 *-weighted dynamic susceptibility contrast MRI technique in brain tumor imaging. J Magn Reson Imaging, 41(2), 296–313. https://doi.org/10.1002/jmri.24648
Shiroishi, Mark S., Gloria Castellazzi, Jerrold L. Boxerman, Francesco D’Amore, Marco Essig, Thanh B. Nguyen, James M. Provenzale, et al. “Principles of T2 *-weighted dynamic susceptibility contrast MRI technique in brain tumor imaging.J Magn Reson Imaging 41, no. 2 (February 2015): 296–313. https://doi.org/10.1002/jmri.24648.
Shiroishi MS, Castellazzi G, Boxerman JL, D’Amore F, Essig M, Nguyen TB, et al. Principles of T2 *-weighted dynamic susceptibility contrast MRI technique in brain tumor imaging. J Magn Reson Imaging. 2015 Feb;41(2):296–313.
Shiroishi, Mark S., et al. “Principles of T2 *-weighted dynamic susceptibility contrast MRI technique in brain tumor imaging.J Magn Reson Imaging, vol. 41, no. 2, Feb. 2015, pp. 296–313. Pubmed, doi:10.1002/jmri.24648.
Shiroishi MS, Castellazzi G, Boxerman JL, D’Amore F, Essig M, Nguyen TB, Provenzale JM, Enterline DS, Anzalone N, Dörfler A, Rovira À, Wintermark M, Law M. Principles of T2 *-weighted dynamic susceptibility contrast MRI technique in brain tumor imaging. J Magn Reson Imaging. 2015 Feb;41(2):296–313.
Journal cover image

Published In

J Magn Reson Imaging

DOI

EISSN

1522-2586

Publication Date

February 2015

Volume

41

Issue

2

Start / End Page

296 / 313

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Neoplasm Recurrence, Local
  • Neoplasm Grading
  • Magnetic Resonance Imaging
  • Humans
  • Hemodynamics
  • Disease Progression
  • Contrast Media
  • Brain Neoplasms
  • 3202 Clinical sciences