Boronic acid porphyrin receptor for ginsenoside sensing.

Journal Article

Ginsenoside detection was pursued through the design of a porphyrin receptor containing two boronic acid units. This receptor was found to undergo different degrees of fluorescence quenching with five ginsenoside guests and an acylated derivative. The trends in the 1:1 binding constants, as well as ESI-HRMS analysis, support a binding mode in which the ginsenoside sugar units are bound to the boronic acid groups, while the steroid core and porphyrin ring participate in hydrophobic interactions.

Full Text

Duke Authors

Cited Authors

  • Hargrove, AE; Reyes, RN; Riddington, I; Anslyn, EV; Sessler, JL

Published Date

  • November 2010

Published In

Volume / Issue

  • 12 / 21

Start / End Page

  • 4804 - 4807

PubMed ID

  • 20860384

Electronic International Standard Serial Number (EISSN)

  • 1523-7052

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol1019647

Language

  • eng