A case series of patients diagnosed with orofacial granulomatosis presenting primarily with dense infiltrates and severe periorbital edema.


Journal Article

Orofacial granulomatosis is a relapsing nonnecrotizing granulomatous syndrome that classically presents with lip and perioral swelling. Over the years, several patients have been referred to the Duke Eye Center Oculoplastics Department for severe, progressive, recurrent eyelid swelling interfering with both their functional vision and their appearance. In this IRB approved retrospective case series, we describe the clinical course of 5 such patients, including their presenting symptoms, diagnosis, and response to treatment. We hope that oculoplastics specialists will consider this entity in the differential diagnosis of periorbital edema and consider initiating localized anti-inflammatory treatment once the diagnosis has been made.

Full Text

Duke Authors

Cited Authors

  • Sabet-Peyman, EJ; Woodward, JA

Published Date

  • November 2014

Published In

Volume / Issue

  • 30 / 6

Start / End Page

  • e151 - e155

PubMed ID

  • 24836447

Pubmed Central ID

  • 24836447

Electronic International Standard Serial Number (EISSN)

  • 1537-2677

Digital Object Identifier (DOI)

  • 10.1097/01.iop.0000440702.85663.e5


  • eng

Conference Location

  • United States