Characterizing weekly self-reported antihypertensive medication nonadherence across repeated occasions.

Published online

Journal Article

BACKGROUND: Little is known about weekly variability in medication nonadherence both between and within persons. PURPOSE: To characterize medication nonadherence across repeated, closely spaced occasions. METHODS: This prospective cohort study comprised four unannounced telephone assessment occasions, each separated by approximately 2 weeks. On each occasion, adult outpatients taking at least a single antihypertensive medication completed a measure of extent of, and reasons for, nonadherence. RESULTS: Two hundred and sixty-one participants completed 871 (83%) of 1,044 occasions. Nonadherence was reported on 152 (17.5%) of 871 occasions by 93 (36%) of 261 participants. The most commonly endorsed reasons for nonadherence were forgetting (39.5%), being busy (23.7%), and traveling (19.7%). Among 219 participants completing at least three occasions, 50% of the variability in extent of nonadherence was a result of within-person fluctuations, and 50% was a result of between-person differences. CONCLUSION: Interventions to reduce nonadherence should be informed by variability in the extent of nonadherence and specific reasons for nonadherence.

Full Text

Duke Authors

Cited Authors

  • Voils, CI; King, HA; Neelon, B; Hoyle, RH; Reeve, BB; Maciejewski, ML; Yancy, WS

Published Date

  • 2014

Published In

Volume / Issue

  • 8 /

Start / End Page

  • 643 - 650

PubMed ID

  • 24855340

Pubmed Central ID

  • 24855340

International Standard Serial Number (ISSN)

  • 1177-889X

Digital Object Identifier (DOI)

  • 10.2147/PPA.S60715


  • eng

Conference Location

  • New Zealand