Transitioning to and from the novel oral anticoagulants: A management strategy for clinicians
Journal Article
Vitamin K antagonists have been the only available oral anticoagulant therapy for decades until the recent introduction of novel (new) oral anticoagulants. This breakthrough provides patients with alternative treatment choices that have predictable pharmacokinetics and do not require routine coagulation monitoring. Though more convenient from patient perspective, these drugs have distinct pharmacological properties that are particularly important to recognize when transitioning anticoagulant therapies. The following review focuses on transitioning to and from the novel oral anticoagulants, employing a practical pharmacokinetic- and pharmacodynamic-based approach. © 2014 Springer Science+Business Media.
Full Text
Duke Authors
Cited Authors
- Abo-Salem, E; Becker, R
Published Date
- 2014
Published In
Volume / Issue
- 37 / 3
Start / End Page
- 372 - 379
International Standard Serial Number (ISSN)
- 0929-5305
Digital Object Identifier (DOI)
- 10.1007/s11239-014-1060-y