Ethical conduct of palliative care research: enhancing communication between investigators and institutional review boards.


Journal Article

Palliative care has faced moral and ethical challenges when conducting research involving human subjects. There are currently no resources to guide institutional review boards (IRBs) in applying standard ethical principles and terms-in a specific way-to palliative care research. Using as a case study a recently completed multisite palliative care clinical trial, this article provides guidance and recommendations for both IRBs and palliative care investigators to facilitate communication and attain the goal of conducting ethical palliative care research and protecting study participants while advancing the science. Beyond identifying current challenges faced by palliative care researchers and IRBs reviewing palliative care research, this article suggests steps that the palliative care research community can take to establish a scientifically sound, stable, productive, and well-functioning relationship between palliative care investigators and the ethical bodies that oversee their work.

Full Text

Cited Authors

  • Abernethy, AP; Capell, WH; Aziz, NM; Ritchie, C; Prince-Paul, M; Bennett, RE; Kutner, JS

Published Date

  • December 2014

Published In

Volume / Issue

  • 48 / 6

Start / End Page

  • 1211 - 1221

PubMed ID

  • 24879998

Pubmed Central ID

  • 24879998

Electronic International Standard Serial Number (EISSN)

  • 1873-6513

International Standard Serial Number (ISSN)

  • 0885-3924

Digital Object Identifier (DOI)

  • 10.1016/j.jpainsymman.2014.05.005


  • eng