Autoimmunity: regulatory B cells--IL-35 and IL-21 regulate the regulators.

Journal Article (Journal Article)

IL-21 regulates the activity and number of IL-10-producing regulatory B cells (B10 cells) that modulate immune responses and limit diverse autoimmune diseases. A new study demonstrates that IL-35 has a similar function. Identifying regulatory circuits that control B10-cell function in vivo might open the door to future treatments for autoimmune diseases.

Full Text

Duke Authors

Cited Authors

  • Tedder, TF; Leonard, WJ

Published Date

  • August 2014

Published In

Volume / Issue

  • 10 / 8

Start / End Page

  • 452 - 453

PubMed ID

  • 24934192

Electronic International Standard Serial Number (EISSN)

  • 1759-4804

Digital Object Identifier (DOI)

  • 10.1038/nrrheum.2014.95


  • eng

Conference Location

  • United States