Applications of RNA interference high-throughput screening technology in cancer biology and virology.
Publication
, Journal Article
Gao, S; Yang, C; Jiang, S; Xu, X-N; Lu, X; He, Y-W; Cheung, A; Wang, H
Published in: Protein Cell
November 2014
RNA interference (RNAi) is an ancient intra-cellular mechanism that regulates gene expression and cell function. Large-scale gene silencing using RNAi high-throughput screening (HTS) has opened an exciting frontier to systematically study gene function in mammalian cells. This approach enables researchers to identify gene function in a given biological context and will provide considerable novel insight. Here, we review RNAi HTS strategies and applications using case studies in cancer biology and virology.
Duke Scholars
Published In
Protein Cell
DOI
EISSN
1674-8018
Publication Date
November 2014
Volume
5
Issue
11
Start / End Page
805 / 815
Location
Germany
Related Subject Headings
- Virus Diseases
- Viral Proteins
- RNA Interference
- Neoplasms
- Molecular Targeted Therapy
- Humans
- Genetic Predisposition to Disease
- Animals
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Gao, S., Yang, C., Jiang, S., Xu, X.-N., Lu, X., He, Y.-W., … Wang, H. (2014). Applications of RNA interference high-throughput screening technology in cancer biology and virology. Protein Cell, 5(11), 805–815. https://doi.org/10.1007/s13238-014-0076-6
Gao, Shan, Chen Yang, Shan Jiang, Xiao-Ning Xu, Xin Lu, You-Wen He, Annie Cheung, and Hui Wang. “Applications of RNA interference high-throughput screening technology in cancer biology and virology.” Protein Cell 5, no. 11 (November 2014): 805–15. https://doi.org/10.1007/s13238-014-0076-6.
Gao S, Yang C, Jiang S, Xu X-N, Lu X, He Y-W, et al. Applications of RNA interference high-throughput screening technology in cancer biology and virology. Protein Cell. 2014 Nov;5(11):805–15.
Gao, Shan, et al. “Applications of RNA interference high-throughput screening technology in cancer biology and virology.” Protein Cell, vol. 5, no. 11, Nov. 2014, pp. 805–15. Pubmed, doi:10.1007/s13238-014-0076-6.
Gao S, Yang C, Jiang S, Xu X-N, Lu X, He Y-W, Cheung A, Wang H. Applications of RNA interference high-throughput screening technology in cancer biology and virology. Protein Cell. 2014 Nov;5(11):805–815.
Published In
Protein Cell
DOI
EISSN
1674-8018
Publication Date
November 2014
Volume
5
Issue
11
Start / End Page
805 / 815
Location
Germany
Related Subject Headings
- Virus Diseases
- Viral Proteins
- RNA Interference
- Neoplasms
- Molecular Targeted Therapy
- Humans
- Genetic Predisposition to Disease
- Animals
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology