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What are the implications of distinct HPV genotypes in women of different ethnic/racial ancestry?

Publication ,  Journal Article
Vidal, AC; Murphy, SK; Hoyo, C
Published in: Journal of Vaccines and Vaccination
January 1, 2014

Invasive cervical cancer incidence and mortality continue to disproportionately affect racial/ethnic minorities, and the distribution of HPV genotypes varies by race/ethnicity, providing a potential explanation for such differences in incidence and mortality. It remains unclear whether such differences could be explained by host genetics or epigenetics that increase susceptibility to particular HPV genotypes, viral genetics, differences in HPV genotypes harbored by different social and/or economic networks, or by differences as simply as function of sexual networks. Determining if race-specific vaccines will benefit some subgroups will depend on addressing these questions. In general, it is our opinion that given population admixture, race/ethnicity based vaccine development may have limited value. Necessary to resolving this question will be the deliberate inclusion of minority populations into observational studies and clinical trials, as well as increase efforts in the study of other less racially admixed populations. © 2014 Vidal AC et al.

Duke Scholars

Published In

Journal of Vaccines and Vaccination

DOI

EISSN

2157-7560

Publication Date

January 1, 2014

Volume

5

Issue

3

Related Subject Headings

  • 1117 Public Health and Health Services
  • 1108 Medical Microbiology
  • 1107 Immunology
 

Citation

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ICMJE
MLA
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Vidal, A. C., Murphy, S. K., & Hoyo, C. (2014). What are the implications of distinct HPV genotypes in women of different ethnic/racial ancestry? Journal of Vaccines and Vaccination, 5(3). https://doi.org/10.4172/2157-7560.1000228
Vidal, A. C., S. K. Murphy, and C. Hoyo. “What are the implications of distinct HPV genotypes in women of different ethnic/racial ancestry?Journal of Vaccines and Vaccination 5, no. 3 (January 1, 2014). https://doi.org/10.4172/2157-7560.1000228.
Vidal AC, Murphy SK, Hoyo C. What are the implications of distinct HPV genotypes in women of different ethnic/racial ancestry? Journal of Vaccines and Vaccination. 2014 Jan 1;5(3).
Vidal, A. C., et al. “What are the implications of distinct HPV genotypes in women of different ethnic/racial ancestry?Journal of Vaccines and Vaccination, vol. 5, no. 3, Jan. 2014. Scopus, doi:10.4172/2157-7560.1000228.
Vidal AC, Murphy SK, Hoyo C. What are the implications of distinct HPV genotypes in women of different ethnic/racial ancestry? Journal of Vaccines and Vaccination. 2014 Jan 1;5(3).

Published In

Journal of Vaccines and Vaccination

DOI

EISSN

2157-7560

Publication Date

January 1, 2014

Volume

5

Issue

3

Related Subject Headings

  • 1117 Public Health and Health Services
  • 1108 Medical Microbiology
  • 1107 Immunology