Hippocampal volume as a predictor of short-term ECT outcomes in older patients with depression


Journal Article

Objective: The authors examined the relationship between hippocampal volume and acute electroconvulsive therapy (ECT) outcomes. Methods: Depression was measured by Montgomery-Asberg Depression Rating Scale (MADRS) scores, and hippocampal volume was assessed by magnetic resonance imaging. Results: After controlling for baseline MADRS score, larger right-hippocampal volume was associated with higher MADRS scores after an index course of ECT. Conclusion: These results are the converse of those obtained in a study assessing the relationship between hippocampal volume and pharmacotherapy. The findings suggest a need for further study in this area. © 2005 American Association for Geriatric Psychiatry.

Full Text

Duke Authors

Cited Authors

  • Lekwauwa, RE; McQuoid, DR; Steffens, DC

Published Date

  • January 1, 2005

Published In

Volume / Issue

  • 13 / 10

Start / End Page

  • 910 - 913

Electronic International Standard Serial Number (EISSN)

  • 1545-7214

International Standard Serial Number (ISSN)

  • 1064-7481

Digital Object Identifier (DOI)

  • 10.1097/00019442-200510000-00011

Citation Source

  • Scopus