Two new cadinane-type sesquiterpenes from the Chinese liverwort Frullania serrata.


Journal Article

Two new cadinane-type sesquiterpenes, frullanic acid (1) and frullanic acid methyl ester (2), together with four known bibenzyls, brittonin B (3), 3,3'-dimethoxy-4,5-methylenedioxybibenzyl (4), 3,4,5,3',4'-penlamethoxybibenzyl (5) and (±)-3-(4'-methoxybenzyl)-5,6-dimethoxyphtbalide (6), were isolated from the Chinese liverwort Frullania serrata. The structures of the new metabolites were elucidated by analysing the spectroscopic data (1D NMR, 2D NMR, HR-ESI-MS and IR). The absolute configurations of compounds 1 and 2 were determined by comparing the experimental and calculated electronic circular dichroism spectra predicted by using time-dependent density functional theory as well as the CD exciton chirality method.

Full Text

Duke Authors

Cited Authors

  • Li, R-J; Zhu, R-X; Zhao, Y; Morris-Natschke, SL; Chen, C-H; Wang, S; Zhang, J-Z; Zhou, J-C; Lou, H-X; Lee, K-H

Published Date

  • 2014

Published In

Volume / Issue

  • 28 / 19

Start / End Page

  • 1519 - 1524

PubMed ID

  • 24969508

Pubmed Central ID

  • 24969508

Electronic International Standard Serial Number (EISSN)

  • 1478-6427

Digital Object Identifier (DOI)

  • 10.1080/14786419.2014.909416


  • eng

Conference Location

  • England