Congenital heart operations performed in the first year of life: does geographic variation exist?

Journal Article (Journal Article;Multicenter Study)

BACKGROUND: Geographic variations associated with surgical intervention for congenital heart disease are ill defined. This study uses a large clinical registry to assess frequency of surgical intervention for various infant congenital heart diseases overall and across US geographic regions. METHODS: Patients younger than 1 year of age in the Society of Thoracic Surgeons Congenital Heart Surgery Database (January 2010 through June 2012) were included. Index operations were classified on the basis of seven major diagnostic groups and 10 specific diagnoses and were compared across geographic regions using a χ(2) test. Region was defined by patient residence. RESULTS: The study included 23,379 patients (94 centers). Septal defects (26.2%) were the most frequently reported diagnostic group, and tetralogy of Fallot (10.6%) was the most frequent specific diagnosis. Significant geographic variation was noted for all seven major diagnostic groups. The proportion of patients undergoing surgery for septal defects varied from 23.9% to 30.2% (p = 0.001); pulmonary venous anomalies, 2.8% to 4.5% (p = 0.03); right heart lesions, 15.7% to 21.4% (p < 0.0001); left heart lesions, 22.7% to 30.4% (p = 0.0002); single-ventricle lesions, 7.3% to 11.4% (p < 0.0001); transposition of the great arteries and double-outlet right ventricle, 9.0% to 15.3% (p < 0.0001); and coronary artery anomalies, 0.4% to 1.4% (p = 0.04). Significant regional variation was also observed for 7 of the 10 specific diagnoses examined. CONCLUSIONS: These data demonstrate significant variation in congenital heart disease diagnostic groups requiring surgery before 1 year of age across US geographic regions.

Full Text

Duke Authors

Cited Authors

  • Husain, SA; Pasquali, SK; Jacobs, JP; Hill, KD; Kim, S; Kane, LC; Calhoon, JH; Jacobs, ML

Published Date

  • September 2014

Published In

Volume / Issue

  • 98 / 3

Start / End Page

  • 912 - 918

PubMed ID

  • 25038009

Pubmed Central ID

  • PMC4527868

Electronic International Standard Serial Number (EISSN)

  • 1552-6259

Digital Object Identifier (DOI)

  • 10.1016/j.athoracsur.2014.04.127


  • eng

Conference Location

  • Netherlands