Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma.


Journal Article

Heterogeneity within tumors is becoming increasingly recognized as an important cause of treatment failure in cancer. Two recent studies use fate-mapping and limiting dilution transplantation assays to identify SRY (sex determining region Y)-box 2 (Sox2) as cancer stem-cell marker and driver of cancer stemness.

Full Text

Cited Authors

  • Becher, OJ; Holland, EC

Published Date

  • September 2014

Published In

Volume / Issue

  • 33 / 18

Start / End Page

  • 1984 - 1986

PubMed ID

  • 25061226

Pubmed Central ID

  • 25061226

Electronic International Standard Serial Number (EISSN)

  • 1460-2075

International Standard Serial Number (ISSN)

  • 0261-4189

Digital Object Identifier (DOI)

  • 10.15252/embj.201489479


  • eng