Colon cancer, version 3.2014.

Journal Article (Journal Article)

The NCCN Guidelines for Colon Cancer address diagnosis, pathologic staging, surgical management, perioperative treatment, posttreatment surveillance, management of recurrent and metastatic disease,and survivorship. This portion of the guidelines focuses on the use of systemic therapy in metastatic disease. The management of metastatic colorectal cancer involves a continuum of care in which patients are exposed sequentially to a variety of active agents, either in combinations or as single agents. Choice of therapy is based on the goals of treatment, the type and timing of prior therapy, the different efficacy and toxicity profiles of the drugs, the mutational status of the tumor, and patient preference.

Full Text

Duke Authors

Cited Authors

  • Benson, AB; Venook, AP; Bekaii-Saab, T; Chan, E; Chen, Y-J; Cooper, HS; Engstrom, PF; Enzinger, PC; Fenton, MJ; Fuchs, CS; Grem, JL; Hunt, S; Kamel, A; Leong, LA; Lin, E; Messersmith, W; Mulcahy, MF; Murphy, JD; Nurkin, S; Rohren, E; Ryan, DP; Saltz, L; Sharma, S; Shibata, D; Skibber, JM; Sofocleous, CT; Stoffel, EM; Stotsky-Himelfarb, E; Willett, CG; Gregory, KM; Freedman-Cass, DA; National Comprehensive Cancer Network,

Published Date

  • July 2014

Published In

Volume / Issue

  • 12 / 7

Start / End Page

  • 1028 - 1059

PubMed ID

  • 24994923

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2014.0099


  • eng

Conference Location

  • United States