Management of anticoagulation agents in trauma patients.
Published
Journal Article (Review)
A lack of consensus on anticoagulant reversal during acute trauma is compounded by an aging population and the expanding spectrum of new anticoagulation agents. Developments in laboratory assays and transfusion medicine, including thromboelastography, recombinant factors, and factor concentrates, have revolutionized care for anticoagulated trauma patients. Accordingly, clinicians must be fully aware of drug mechanisms, assays to determine drug activity, and appropriate reversal strategies for patients on anticoagulants. Drugs include vitamin K antagonists, direct thrombin inhibitors, direct factor Xa inhibitors, low molecular weight heparin, and antiplatelet agents. This article discusses the appropriate assessment and management of trauma patients receiving these agents.
Full Text
Duke Authors
Cited Authors
- McCoy, CC; Lawson, JH; Shapiro, ML
Published Date
- September 2014
Published In
Volume / Issue
- 34 / 3
Start / End Page
- 563 - 574
PubMed ID
- 25168942
Pubmed Central ID
- 25168942
Electronic International Standard Serial Number (EISSN)
- 1557-9832
Digital Object Identifier (DOI)
- 10.1016/j.cll.2014.06.013
Language
- eng
Conference Location
- United States