Clinical use of the activated partial thromboplastin time and prothrombin time for screening: a review of the literature and current guidelines for testing.

Other Article (Journal Article;Review)

Although the activated partial thromboplastin time, prothrombin time, and international normalized ratio are widely used in routine preoperative testing, these hemostatic tests are not reliable predictors of perioperative bleeding in patients without known bleeding risk factors. In contrast, a preoperative bleeding history and physical examination are usually obtained in an attempt to identify important bleeding risk factors. However, these coagulation tests are used extensively for monitoring anticoagulation with different pharmacologic agents.

Full Text

Duke Authors

Cited Authors

  • Levy, JH; Szlam, F; Wolberg, AS; Winkler, A

Published Date

  • September 2014

Published In

Volume / Issue

  • 34 / 3

Start / End Page

  • 453 - 477

PubMed ID

  • 25168937

Electronic International Standard Serial Number (EISSN)

  • 1557-9832

Digital Object Identifier (DOI)

  • 10.1016/j.cll.2014.06.005


  • eng

Conference Location

  • United States