Sleep impairment, mood symptoms, and psychosocial functioning in adolescent bipolar disorder.

Journal Article (Journal Article)

Few empirical studies have investigated the role of sleep impairment in the course of adolescent bipolar spectrum disorders (BSD). The present study examined the longitudinal associations between sleep disruption, mood symptom severity, and psychosocial functioning in a 2-year follow-up of patients with adolescent BSD. Fifty-three adolescents with BSD (mean [S.D.] age: 14.6 [1.6]) participated in a two-site randomized trial of family focused treatment for adolescents (FFT-A) or enhanced care, a briefer psychoeducational treatment; both treatments were administered with pharmacotherapy. Sleep disturbance was assessed with the Adolescent Sleep Habits Questionnaire (ASHQ) filled out by patients every 6 weeks in the first study year and every 3 months in the second year. Main outcomes included clinician-rated measures of mania, depression and psychosocial impairment over 2 years. Sleep impairment was significantly associated with mania and depression severity scores and psychosocial impairment ratings across the 2-year follow-up. Despite its efficaciousness in reducing mood symptoms, FFT-A was not more effective than enhanced care in improving sleep habits. Sleep impairment may play a substantial role in the course of adolescent BSD. Youth with BSDs may benefit from targeted psychosocial interventions that emphasize sleep regularity.

Full Text

Duke Authors

Cited Authors

  • Lunsford-Avery, JR; Judd, CM; Axelson, DA; Miklowitz, DJ

Published Date

  • December 30, 2012

Published In

Volume / Issue

  • 200 / 2-3

Start / End Page

  • 265 - 271

PubMed ID

  • 22884306

Pubmed Central ID

  • PMC3513660

Electronic International Standard Serial Number (EISSN)

  • 1872-7123

Digital Object Identifier (DOI)

  • 10.1016/j.psychres.2012.07.037


  • eng

Conference Location

  • Ireland