A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting.
Journal Article (Journal Article)
Metal chelators masked with protecting groups for targeted release have the potential to conditionally modulate cellular metals. We report a new route to prepare cis-cinnamate protecting groups that enabled development of a prochelator with chemical stimulus response, fluorescent reporting and active compound release in a single structure.
Full Text
Duke Authors
Cited Authors
- Franks, AT; Franz, KJ
Published Date
- October 2014
Published In
Volume / Issue
- 50 / 77
Start / End Page
- 11317 - 11320
PubMed ID
- 25116739
Pubmed Central ID
- PMC4154376
Electronic International Standard Serial Number (EISSN)
- 1364-548X
International Standard Serial Number (ISSN)
- 1359-7345
Digital Object Identifier (DOI)
- 10.1039/c4cc05076b
Language
- eng