A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting.

Journal Article

Metal chelators masked with protecting groups for targeted release have the potential to conditionally modulate cellular metals. We report a new route to prepare cis-cinnamate protecting groups that enabled development of a prochelator with chemical stimulus response, fluorescent reporting and active compound release in a single structure.

Full Text

Duke Authors

Cited Authors

  • Franks, AT; Franz, KJ

Published Date

  • October 2014

Published In

Volume / Issue

  • 50 / 77

Start / End Page

  • 11317 - 11320

PubMed ID

  • 25116739

Electronic International Standard Serial Number (EISSN)

  • 1364-548X

International Standard Serial Number (ISSN)

  • 1359-7345

Digital Object Identifier (DOI)

  • 10.1039/c4cc05076b

Language

  • eng