Pharmacogenetics of antiplatelet therapy
Publication
, Journal Article
Daly, PL; Becker, RC
Published in: Current Atherosclerosis Reports
2014
There has been substantial progress toward understanding and investigating the specific genetic factors that influence interindividual variations in platelet-directed therapy. There has also been substantial progress toward better understanding of the pharmacogenetics of drug metabolism and phamacodynamic response to platelet antagonists. We summarize the relationship between genetic polymorphisms, response to platelet antagonists, and clinical impact on patient treatment for the commonly used antiplatelet drugs. The challenge faced in translating genotype identification into improved clinical outcomes reflects the complexity involved in the genomic influence on drug metabolism and activation. © Springer Science+Business Media 2014.
Duke Scholars
Published In
Current Atherosclerosis Reports
DOI
ISSN
1523-3804
Publication Date
2014
Volume
16
Issue
5
Related Subject Headings
- Cardiovascular System & Hematology
- 1102 Cardiorespiratory Medicine and Haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Daly, P. L., & Becker, R. C. (2014). Pharmacogenetics of antiplatelet therapy. Current Atherosclerosis Reports, 16(5). https://doi.org/10.1007/s11883-014-0411-7
Daly, P. L., and R. C. Becker. “Pharmacogenetics of antiplatelet therapy.” Current Atherosclerosis Reports 16, no. 5 (2014). https://doi.org/10.1007/s11883-014-0411-7.
Daly PL, Becker RC. Pharmacogenetics of antiplatelet therapy. Current Atherosclerosis Reports. 2014;16(5).
Daly, P. L., and R. C. Becker. “Pharmacogenetics of antiplatelet therapy.” Current Atherosclerosis Reports, vol. 16, no. 5, 2014. Scival, doi:10.1007/s11883-014-0411-7.
Daly PL, Becker RC. Pharmacogenetics of antiplatelet therapy. Current Atherosclerosis Reports. 2014;16(5).
Published In
Current Atherosclerosis Reports
DOI
ISSN
1523-3804
Publication Date
2014
Volume
16
Issue
5
Related Subject Headings
- Cardiovascular System & Hematology
- 1102 Cardiorespiratory Medicine and Haematology