Immunological targeting of cytomegalovirus for glioblastoma therapy.

Journal Article (Journal Article)

Human cytomegalovirus (CMV) is purportedly present in glioblastoma (GBM) while absent from the normal brain, making CMV antigens potentially ideal immunological anti-GBM targets. We recently demonstrated that patient-derived CMV pp65-specific T cells are capable of recognizing and killing autologous GBM tumor cells. This data supports CMV antigen-directed immunotherapies against GBM.

Full Text

Duke Authors

Cited Authors

  • Nair, SK; Sampson, JH; Mitchell, DA

Published Date

  • 2014

Published In

Volume / Issue

  • 3 /

Start / End Page

  • e29289 -

PubMed ID

  • 25101224

Pubmed Central ID

  • PMC4121337

International Standard Serial Number (ISSN)

  • 2162-4011

Digital Object Identifier (DOI)

  • 10.4161/onci.29289


  • eng

Conference Location

  • United States