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Colorectal cancer with potentially resectable hepatic metastases: optimizing treatment.

Publication ,  Journal Article
Worni, M; Shah, KN; Clary, BM
Published in: Curr Oncol Rep
October 2014

Colorectal cancer is a common malignancy and often presents with synchronous or metachronous distant spread. For patients with hepatic metastases, resection is the principal curative option. Liberalization of the indications for hepatic resection has introduced a number of challenges related to the size, distribution, and number of metastases as well as the condition of the future liver remnant. Advances in systemic therapy have solidified its role as both an important adjunct to surgery and also for many patients as a mechanism to facilitate resection. In patients whose disease is marginally resectable as a consequence of the distribution of hepatic lesions that precludes complete resection or out of concern for the future liver remnant, a number of strategies have been advocated, including prehepatectomy systemic therapy, staged surgical approaches, ablative technologies, and preoperative portal vein embolization. It is the purpose of this review to discuss ways in which to optimize the treatment of patients with potentially resectable disease, specifically those who are judged to have "borderline" resectable situations.

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Published In

Curr Oncol Rep

DOI

EISSN

1534-6269

Publication Date

October 2014

Volume

16

Issue

10

Start / End Page

407

Location

United States

Related Subject Headings

  • Tumor Burden
  • Treatment Outcome
  • Prognosis
  • Preoperative Care
  • Practice Guidelines as Topic
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Neoplasm Recurrence, Local
  • Neoadjuvant Therapy
  • Liver Neoplasms
 

Citation

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Worni, M., Shah, K. N., & Clary, B. M. (2014). Colorectal cancer with potentially resectable hepatic metastases: optimizing treatment. Curr Oncol Rep, 16(10), 407. https://doi.org/10.1007/s11912-014-0407-z
Worni, Mathias, Kevin N. Shah, and Bryan M. Clary. “Colorectal cancer with potentially resectable hepatic metastases: optimizing treatment.Curr Oncol Rep 16, no. 10 (October 2014): 407. https://doi.org/10.1007/s11912-014-0407-z.
Worni M, Shah KN, Clary BM. Colorectal cancer with potentially resectable hepatic metastases: optimizing treatment. Curr Oncol Rep. 2014 Oct;16(10):407.
Worni, Mathias, et al. “Colorectal cancer with potentially resectable hepatic metastases: optimizing treatment.Curr Oncol Rep, vol. 16, no. 10, Oct. 2014, p. 407. Pubmed, doi:10.1007/s11912-014-0407-z.
Worni M, Shah KN, Clary BM. Colorectal cancer with potentially resectable hepatic metastases: optimizing treatment. Curr Oncol Rep. 2014 Oct;16(10):407.
Journal cover image

Published In

Curr Oncol Rep

DOI

EISSN

1534-6269

Publication Date

October 2014

Volume

16

Issue

10

Start / End Page

407

Location

United States

Related Subject Headings

  • Tumor Burden
  • Treatment Outcome
  • Prognosis
  • Preoperative Care
  • Practice Guidelines as Topic
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Neoplasm Recurrence, Local
  • Neoadjuvant Therapy
  • Liver Neoplasms