Potential applications of pharmacogenomics to heart failure therapies.

Journal Article (Journal Article;Review)

Pharmacogenomics explores one drug's varying effects on different patient genotypes. A better understanding of genomic variation's contribution to drug response can impact 4 arenas in heart failure (HF): (1) identification of patients most likely to receive benefit from therapy, (2) risk stratify patients for risk of adverse events, (3) optimize dosing of drugs, and (4) steer future clinical trial design and drug development. In this review, the authors explore the potential applications of pharmacogenomics in patients with HF in the context of these categories.

Full Text

Duke Authors

Cited Authors

  • Parikh, KS; Ahmad, T; Fiuzat, M

Published Date

  • October 2014

Published In

Volume / Issue

  • 10 / 4

Start / End Page

  • 599 - 606

PubMed ID

  • 25217435

International Standard Serial Number (ISSN)

  • 1551-7136

Digital Object Identifier (DOI)

  • 10.1016/j.hfc.2014.07.007


  • eng

Conference Location

  • United States