The effects of total knee arthroplasty on physical functioning and health among the under age 65 population


Journal Article

Objectives This study examined the effects of total knee arthroplasty on six measures of physical functioning, self-rated health, pain, earnings, and employment status among US adults aged 51 to 63 years at baseline. Methods Data came from the Health and Retirement Study, a nationally representative longitudinal study conducted biannually. The analysis sample consisted of individuals aged 51 to 63 years at baseline with arthritis who were resurveyed at 2-year intervals from 1996 to 2010. Propensity score matching was used to compare outcomes of persons receiving total knee arthroplasty (TKA) with those of matched controls. Six measures of physical functioning were examined: lower-body mobility problems, instrumental activities of daily living limitations, activities of daily living limitations, and large muscle, fine motor, and gross motor limitations. Self-rated health and pain were also examined. The two employment-related outcomes were earnings and employment status. Results Receipt of TKA was associated with better outcomes for several measures of physical functioning, especially mobility limitations, pain, and self-rated health. Receipt of TKA was not associated with increased earnings or employment. Conclusions Receipt of TKA yields important improvements in physical function among persons with an arthritis diagnosis who received the procedure before reaching the age of 65 years. This study contributes to knowledge about the benefits of TKA in a community setting among nonelderly recipients of TKA. © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR).

Full Text

Duke Authors

Published Date

  • January 1, 2014

Published In

Volume / Issue

  • 17 / 5

Start / End Page

  • 605 - 610

Electronic International Standard Serial Number (EISSN)

  • 1524-4733

International Standard Serial Number (ISSN)

  • 1098-3015

Digital Object Identifier (DOI)

  • 10.1016/j.jval.2014.04.004

Citation Source

  • Scopus