Genetic/familial high-risk assessment: breast and ovarian, version 1.2014.

Journal Article (Journal Article)

During the past few years, several genetic aberrations that may contribute to increased risks for development of breast and/or ovarian cancers have been identified. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian focus specifically on the assessment of genetic mutations in BRCA1/BRCA2, TP53, and PTEN, and recommend approaches to genetic testing/counseling and management strategies in individuals with these mutations. This portion of the NCCN Guidelines includes recommendations regarding diagnostic criteria and management of patients with Cowden Syndrome/PTEN hamartoma tumor syndrome.

Full Text

Duke Authors

Cited Authors

  • Daly, MB; Pilarski, R; Axilbund, JE; Buys, SS; Crawford, B; Friedman, S; Garber, JE; Horton, C; Kaklamani, V; Klein, C; Kohlmann, W; Kurian, A; Litton, J; Madlensky, L; Marcom, PK; Merajver, SD; Offit, K; Pal, T; Pasche, B; Reiser, G; Shannon, KM; Swisher, E; Voian, NC; Weitzel, JN; Whelan, A; Wiesner, GL; Dwyer, MA; Kumar, R; National comprehensive cancer network,

Published Date

  • September 2014

Published In

Volume / Issue

  • 12 / 9

Start / End Page

  • 1326 - 1338

PubMed ID

  • 25190698

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2014.0127


  • eng

Conference Location

  • United States