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Nonlinear image blending for dual-energy MDCT of the abdomen: can image quality be preserved if the contrast medium dose is reduced?

Publication ,  Journal Article
Mileto, A; Ramirez-Giraldo, JC; Marin, D; Alfaro-Cordoba, M; Eusemann, CD; Scribano, E; Blandino, A; Mazziotti, S; Ascenti, G
Published in: AJR Am J Roentgenol
October 2014

OBJECTIVE: The objective of this study was to compare the image quality of a dual-energy nonlinear image blending technique at reduced load of contrast medium with a simulated 120-kVp linear blending technique at a full dose during portal venous phase MDCT of the abdomen. SUBJECTS AND METHODS: Forty-five patients (25 men, 20 women; mean age, 65.6 ± 9.7 [SD] years; mean body weight, 74.9 ± 12.4 kg) underwent contrast-enhanced single-phase dual-energy CT of the abdomen by a random assignment to one of three different contrast medium (iomeprol 400) dose injection protocols: 1.3, 1.0, or 0.65 mL/kg of body weight. The contrast-to-noise ratio (CNR) and noise at the portal vein, liver, aorta, and kidney were compared among the different datasets using the ANOVA. Three readers qualitatively assessed all datasets in a blinded and independent fashion. RESULTS: Nonlinear blended images at a 25% reduced dose allowed a significant improvement in CNR (p < 0.05 for all comparisons), compared with simulated 120-kVp linear blended images at a full dose. No statistically significant difference existed in CNR and noise between the nonlinear blended images at a 50% reduced dose and the simulated 120-kVp linear blended images at a full dose. Nonlinear blended images at a 50% reduced dose were considered in all cases to have acceptable image quality. CONCLUSION: The dual-energy nonlinear image blending technique allows reducing the dose of contrast medium up to 50% during portal venous phase imaging of the abdomen while preserving image quality.

Duke Scholars

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

October 2014

Volume

203

Issue

4

Start / End Page

838 / 845

Location

United States

Related Subject Headings

  • Subtraction Technique
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiography, Dual-Energy Scanned Projection
  • Radiography, Abdominal
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiographic Image Enhancement
  • Nuclear Medicine & Medical Imaging
  • Nonlinear Dynamics
  • Multidetector Computed Tomography
 

Citation

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MLA
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Mileto, A., Ramirez-Giraldo, J. C., Marin, D., Alfaro-Cordoba, M., Eusemann, C. D., Scribano, E., … Ascenti, G. (2014). Nonlinear image blending for dual-energy MDCT of the abdomen: can image quality be preserved if the contrast medium dose is reduced? AJR Am J Roentgenol, 203(4), 838–845. https://doi.org/10.2214/AJR.13.12179
Mileto, Achille, Juan Carlos Ramirez-Giraldo, Daniele Marin, Marcela Alfaro-Cordoba, Christian D. Eusemann, Emanuele Scribano, Alfredo Blandino, Silvio Mazziotti, and Giorgio Ascenti. “Nonlinear image blending for dual-energy MDCT of the abdomen: can image quality be preserved if the contrast medium dose is reduced?AJR Am J Roentgenol 203, no. 4 (October 2014): 838–45. https://doi.org/10.2214/AJR.13.12179.
Mileto A, Ramirez-Giraldo JC, Marin D, Alfaro-Cordoba M, Eusemann CD, Scribano E, et al. Nonlinear image blending for dual-energy MDCT of the abdomen: can image quality be preserved if the contrast medium dose is reduced? AJR Am J Roentgenol. 2014 Oct;203(4):838–45.
Mileto, Achille, et al. “Nonlinear image blending for dual-energy MDCT of the abdomen: can image quality be preserved if the contrast medium dose is reduced?AJR Am J Roentgenol, vol. 203, no. 4, Oct. 2014, pp. 838–45. Pubmed, doi:10.2214/AJR.13.12179.
Mileto A, Ramirez-Giraldo JC, Marin D, Alfaro-Cordoba M, Eusemann CD, Scribano E, Blandino A, Mazziotti S, Ascenti G. Nonlinear image blending for dual-energy MDCT of the abdomen: can image quality be preserved if the contrast medium dose is reduced? AJR Am J Roentgenol. 2014 Oct;203(4):838–845.

Published In

AJR Am J Roentgenol

DOI

EISSN

1546-3141

Publication Date

October 2014

Volume

203

Issue

4

Start / End Page

838 / 845

Location

United States

Related Subject Headings

  • Subtraction Technique
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiography, Dual-Energy Scanned Projection
  • Radiography, Abdominal
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiographic Image Enhancement
  • Nuclear Medicine & Medical Imaging
  • Nonlinear Dynamics
  • Multidetector Computed Tomography