DNA bioassay-on-chip using SERS detection for dengue diagnosis.
A novel DNA bioassay-on-chip using surface-enhanced Raman scattering (SERS) on a bimetallic nanowave chip is presented. In this bioassay, SERS signals were measured after a single reaction on the chip's surface without any washing step, making it simple-to-use and reducing the reagent cost. Using the technique, specific oligonucleotide sequences of the dengue virus 4 were detected.
Ngo, HT; Wang, H-N; Fales, AM; Nicholson, BP; Woods, CW; Vo-Dinh, T
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