Simplified microneutralization test for serotyping adenovirus isolates.


Journal Article

A simplified microneutralization procedure is described that uses an empirically determined virus challenge dose, a single dilution of antiserum, and observation of cytopathic effect to determine the adenovirus serotype. The simplified test has faster turnaround time and was 96% concordant with a confirmatory test using serial dilutions of type-specific sera. This method will find utility in high-volume serotyping work.

Full Text

Duke Authors

Cited Authors

  • Malasig, MD; Goswami, PR; Crawford-Miksza, LK; Schnurr, DP; Gray, GC

Published Date

  • August 2001

Published In

Volume / Issue

  • 39 / 8

Start / End Page

  • 2984 - 2986

PubMed ID

  • 11474029

Pubmed Central ID

  • 11474029

International Standard Serial Number (ISSN)

  • 0095-1137

Digital Object Identifier (DOI)

  • 10.1128/JCM.39.8.2984-2986.2001


  • eng

Conference Location

  • United States