The risk of measles, mumps, and varicella among young adults: a serosurvey of US Navy and Marine Corps recruits.

Published

Journal Article

OBJECTIVES: To assess the risk of epidemic transmission and to guide immunization policy, the seroprevalence of antibody to measles, mumps, and varicella was determined in a group of young adults. METHODS: A cross-sectional study of 1533 US Navy and Marine Corps recruits was conducted in June 1989. Antibody status was determined with commercially available enzyme-linked immunosorbent assays. RESULTS: Direct sex and race adjustment to the 15- to 29-year-old US population resulted in seronegativity rates of 17.8% for measles, 12.3% for mumps, and 6.7% for varicella. Measles and mumps seronegativity rates were higher among Whites whereas varicella seronegativity was higher among non-Whites. Recruits enlisting from outside the 50 US states, especially those from island territories, were more likely to lack varicella antibody. The sensitivity of a positive history of vaccination or disease in predicting antibody status was less than 90% for all diseases. CONCLUSIONS: These results suggest a continued potential for epidemics, especially of measles, and the need for mandatory immunization policies. Immigrants to the United States, especially those from island territories, may be a high-risk group that could benefit from varicella vaccination.

Full Text

Duke Authors

Cited Authors

  • Struewing, JP; Hyams, KC; Tueller, JE; Gray, GC

Published Date

  • December 1993

Published In

Volume / Issue

  • 83 / 12

Start / End Page

  • 1717 - 1720

PubMed ID

  • 8259801

Pubmed Central ID

  • 8259801

Electronic International Standard Serial Number (EISSN)

  • 1541-0048

International Standard Serial Number (ISSN)

  • 0090-0036

Digital Object Identifier (DOI)

  • 10.2105/ajph.83.12.1717

Language

  • eng