Diagnosis of metastatic renal cell carcinoma on fine-needle aspiration cytology.

Journal Article (Journal Article;Review)

Fine-needle aspiration has assumed an increasingly important role in the diagnosis and management of patients with advanced stage cancer. Given its predilection for metastases to distant sites and organs at the time of presentation, metastatic renal cell carcinoma (RCC) is not infrequently encountered in the setting of fine-needle aspiration for initial diagnosis. In some instances, fine-needle aspiration may be the only opportunity to obtain diagnostic tissue to diagnose and subclassify RCC. Therefore, cytopathologists and cytotechnologists should be familiar with and recognize the cytomorphology of RCC and the ancillary studies that can be used to confirm and subclassify RCC. Herein, we describe a case of metastatic RCC initially diagnosed on fine-needle aspiration, discuss the cytomorphologic features of RCC subtypes, and review pertinent ancillary immunohistochemical and cytogenetic adjuncts.

Full Text

Duke Authors

Cited Authors

  • Lew, M; Foo, W-C; Roh, MH

Published Date

  • October 2014

Published In

Volume / Issue

  • 138 / 10

Start / End Page

  • 1278 - 1285

PubMed ID

  • 25268189

Electronic International Standard Serial Number (EISSN)

  • 1543-2165

Digital Object Identifier (DOI)

  • 10.5858/arpa.2014-0283-CC


  • eng

Conference Location

  • United States