Enantioselective intramolecular hydroamination of unactivated alkenes catalyzed by mono- and bis(gold) phosphine complexes

Journal Article

A 1:2 mixture of (P1)(AuCl)2[P1=(S)-DTBM-MeO-BIPHEP] and silver tetrafluoroborate (AgBF4) in methanol catalyzes the intramolecular hydroamination of unactivated alkenes with carbamates and ureas to form pyrrolidine derivatives with up to 85% ee.

Full Text

Duke Authors

Cited Authors

  • Lee, SD; Timmerman, JC; Widenhoefer, RA

Published Date

  • October 1, 2014

Published In

Volume / Issue

  • 356 / 14-15

Start / End Page

  • 3187 - 3192

Published By

Electronic International Standard Serial Number (EISSN)

  • 1615-4169

International Standard Serial Number (ISSN)

  • 1615-4150

Digital Object Identifier (DOI)

  • 10.1002/adsc.201400268

Language

  • eng

Citation Source

  • Scopus