Cardiorespiratory interactions: the relationship between mechanical ventilation and hemodynamics.


Journal Article (Review)

The overall goal of the cardiorespiratory system is to provide the organs and tissues of the body with an adequate supply of oxygen in relation to oxygen consumption. An understanding of the complex physiologic interactions between the respiratory and cardiac systems is essential to optimal patient management. Alterations in intrathoracic pressure are transmitted to the heart and lungs and can dramatically alter cardiovascular performance, with significant differences existing between the physiologic response of the right and left ventricles to changes in intrathoracic pressure. In terms of cardiorespiratory interactions, the clinician should titrate the mean airway pressure to optimize the balance between mean lung volume (ie, arterial oxygenation) and ventricular function (ie, global cardiac output), minimize pulmonary vascular resistance, and routinely monitor cardiorespiratory parameters closely. Oxygen delivery to all organs and tissues of the body should be optimized, but not necessarily maximized. The heart and lungs are, obviously, connected anatomically but also physiologically in a complex relationship.

Full Text

Cited Authors

  • Cheifetz, IM

Published Date

  • December 2014

Published In

Volume / Issue

  • 59 / 12

Start / End Page

  • 1937 - 1945

PubMed ID

  • 25389353

Pubmed Central ID

  • 25389353

Electronic International Standard Serial Number (EISSN)

  • 1943-3654

International Standard Serial Number (ISSN)

  • 0020-1324

Digital Object Identifier (DOI)

  • 10.4187/respcare.03486


  • eng