The human mycobiome.

Published online

Journal Article (Review)

Fungi are fundamental to the human microbiome, the collection of microbes distributed across and within the body, and the microbiome has been shown, in total, to modify fundamental human physiology, including energy acquisition, vitamin-cofactor availability, xenobiotic metabolism, immune development and function, and even neurological development and behavior. Here, a comprehensive review of current knowledge about the mycobiome, the collective of fungi within the microbiome, highlights methods for its study, diversity between body sites, and dynamics during human development, health, and disease. Early-stage studies show interactions between the mycobiome and other microbes, with host physiology, and in pathogenic and mutualistic phenotypes. Current research portends a vital role for the mycobiome in human health and disease.

Full Text

Cited Authors

  • Seed, PC

Published Date

  • November 10, 2014

Published In

Volume / Issue

  • 5 / 5

Start / End Page

  • a019810 -

PubMed ID

  • 25384764

Pubmed Central ID

  • 25384764

Electronic International Standard Serial Number (EISSN)

  • 2157-1422

Digital Object Identifier (DOI)

  • 10.1101/cshperspect.a019810

Language

  • eng

Conference Location

  • United States