Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy.
Other Article (Journal Article)
This commentary describes a rationale for the use of breakthrough viruses from clinical trial participants to assess neutralizing antibodies as a correlate of HIV-1 vaccine efficacy. The rationale is based on principles of a genetic sieve analysis, where the 2 analyses may be cooperative for delineating neutralizing antibodies as a mechanistic correlate of protection.
Full Text
Duke Authors
Cited Authors
- Montefiori, DC
Published Date
- 2014
Published In
Volume / Issue
- 10 / 8
Start / End Page
- 2507 - 2511
PubMed ID
- 25424964
Electronic International Standard Serial Number (EISSN)
- 2164-554X
Digital Object Identifier (DOI)
- 10.4161/hv.28950
Language
- eng
Conference Location
- United States