Mindfulness meditation alleviates fibromyalgia symptoms in women: results of a randomized clinical trial.

Journal Article (Journal Article)

BACKGROUND: Several recent reviews have evaluated evidence on the efficacy of Mindfulness-Based Stress Reduction (MBSR) among fibromyalgia sufferers, and concluded that more research should test effects on both psychological and physiological functioning. PURPOSE: We conducted a randomized prospective trial of MBSR among female fibromyalgia patients. METHODS: Effects on perceived stress, pain, sleep quality, fatigue, symptom severity, and salivary cortisol were tested in treatment (n=51) versus wait-list control participants (n=40) using data at baseline, post-program, and 2-month follow-up. RESULTS: Analyses revealed that MBSR significantly reduced perceived stress, sleep disturbance, and symptom severity, with gains maintained at follow-up. Greater home practice at follow-up was associated with reduced symptom severity. MBSR did not significantly alter pain, physical functioning, or cortisol profiles. CONCLUSION: MBSR ameliorated some of the major symptoms of fibromyalgia and reduced subjective illness burden. Further exploration of MBSR effects on physiological stress responses is warranted. These results support use of MBSR as a complementary treatment for women with fibromyalgia ( ISRCTN: 34628811).

Full Text

Duke Authors

Cited Authors

  • Cash, E; Salmon, P; Weissbecker, I; Rebholz, WN; Bayley-Veloso, R; Zimmaro, LA; Floyd, A; Dedert, E; Sephton, SE

Published Date

  • June 2015

Published In

Volume / Issue

  • 49 / 3

Start / End Page

  • 319 - 330

PubMed ID

  • 25425224

Pubmed Central ID

  • 25425224

Electronic International Standard Serial Number (EISSN)

  • 1532-4796

Digital Object Identifier (DOI)

  • 10.1007/s12160-014-9665-0


  • eng

Conference Location

  • England