Intracranial vertebral artery dissections: evolving perspectives.


Journal Article

Intracranial vertebral artery dissection (VAD) represents the underlying etiology in a significant percentage of posterior circulation ischemic strokes and subarachnoid hemorrhages. These lesions are particularly challenging in their diagnosis, management, and in the prediction of long-term outcome. Advances in the understanding of underlying processes leading to dissection, as well as the evolution of modern imaging techniques are discussed. The data pertaining to medical management of intracranial VADs, with emphasis on anticoagulants and antiplatelet agents, is reviewed. Surgical intervention is discussed, including, the selection of operative candidates, open and endovascular procedures, and potential complications. The evolution of endovascular technology and techniques is highlighted.

Full Text

Duke Authors

Cited Authors

  • Ali, MS; Amenta, PS; Starke, RM; Jabbour, PM; Gonzalez, LF; Tjoumakaris, SI; Flanders, AE; Rosenwasser, RH; Dumont, AS

Published Date

  • December 2012

Published In

Volume / Issue

  • 18 / 4

Start / End Page

  • 469 - 483

PubMed ID

  • 23217643

Pubmed Central ID

  • 23217643

International Standard Serial Number (ISSN)

  • 1591-0199

Digital Object Identifier (DOI)

  • 10.1177/159101991201800414


  • eng

Conference Location

  • United States