A true malignant schwannoma of the eighth cranial nerve: case report.

Journal Article (Journal Article)

OBJECTIVE: The clinical presentation, pathology, treatment, and outcome of a 43-year-old woman with a malignant peripheral nerve sheath tumor arising from a benign schwannoma of the eighth cranial nerve are presented. CLINICAL PRESENTATION: Initially, the tumor was debulked. After finding malignant areas within the benign tumor, it was considered to be a malignant transformation of a previously benign tumor. INTERVENTION: Aggressive total resection was obtained during a second-stage procedure. Postoperatively, the tumor bed was radiated for palliation. CONCLUSION: Despite surgery, radiation, and chemotherapy, the patient died rapidly as a result of disseminated metastatic disease.

Full Text

Duke Authors

Cited Authors

  • Gonzalez, LF; Lekovic, GP; Eschbacher, J; Coons, S; Spetzler, RF

Published Date

  • August 2007

Published In

Volume / Issue

  • 61 / 2

Start / End Page

  • E421 - E422

PubMed ID

  • 17762727

Pubmed Central ID

  • 17762727

Electronic International Standard Serial Number (EISSN)

  • 1524-4040

Digital Object Identifier (DOI)

  • 10.1227/01.NEU.0000255517.19709.FC


  • eng

Conference Location

  • United States