Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis.

Published

Journal Article (Review)

We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane methodology. Oxygen therapy reduced dyspnoea when compared with medical air; standardised mean difference -0.37 (95% CI -0.50 to -0.24; I(2)=14%). In a priori subgroup and sensitivity analyses, dyspnoea was reduced by continuous oxygen during exertion but not short-burst oxygen therapy. Continuous exertional oxygen can relieve dyspnoea in mildly or non-hypoxemic COPD, but evidence from larger clinical trials is needed.

Full Text

Duke Authors

Cited Authors

  • Uronis, HE; Ekström, MP; Currow, DC; McCrory, DC; Samsa, GP; Abernethy, AP

Published Date

  • May 2015

Published In

Volume / Issue

  • 70 / 5

Start / End Page

  • 492 - 494

PubMed ID

  • 25472664

Pubmed Central ID

  • 25472664

Electronic International Standard Serial Number (EISSN)

  • 1468-3296

International Standard Serial Number (ISSN)

  • 0040-6376

Digital Object Identifier (DOI)

  • 10.1136/thoraxjnl-2014-205720

Language

  • eng