Retinopathy of prematurity risk prediction for infants with birth weight less than 1251 grams.

Journal Article (Clinical Trial;Journal Article)

OBJECTIVE: To predict retinopathy of prematurity (ROP) exam findings among infants with birth weight <1251 g from 32-40 weeks postmenstrual age (PMA). STUDY DESIGN: Secondary analysis of 3714 eye exams from 1239 infants. RESULTS: The likelihood of developing type 1 ROP by 40 weeks PMA varied by gestational age (GA) (P < .001), from 33% for ≤25 weeks, 10% for 26 or 27 weeks, 4% for 28 or 29 weeks, and none for ≥30 weeks. By 40 weeks PMA, 51% with GA ≤27 weeks still needed subsequent exams. Previous exam findings, GA, and PMA were predictive of the development of type 1 ROP (area under the curve, 0.78) or mature retina (area under the curve, 0.85). CONCLUSIONS: This analysis provides the opportunity for development of an ROP approach to estimate resource needs in the neonatal intensive care unit and to facilitate communication with families when planning discharge or transfer.

Full Text

Duke Authors

Cited Authors

  • Kemper, AR; Wade, KC; Hornik, CP; Ying, G-S; Baumritter, A; Quinn, GE; Telemedicine Approaches to Evaluating Acute-phase Retinopathy of Prematurity (e-ROP) Study Cooperative Group,

Published Date

  • February 2015

Published In

Volume / Issue

  • 166 / 2

Start / End Page

  • 257 - 61.e2

PubMed ID

  • 25449219

Pubmed Central ID

  • PMC4308554

Electronic International Standard Serial Number (EISSN)

  • 1097-6833

Digital Object Identifier (DOI)

  • 10.1016/j.jpeds.2014.09.069


  • eng

Conference Location

  • United States