Cell polarity: netrin calms an excitable system.
Published
Journal Article
In a tractable model for cell invasion, the Caenorhabditis elegans anchor cell migrates through basement membranes towards a polarity cue provided by netrin. A new study reveals that the anchor cell polarity network can break symmetry and oscillate in the absence of netrin, suggesting the presence of interlinked positive and negative feedback loops, which are common in polarity pathways.
Full Text
Duke Authors
Cited Authors
- McClure, AW; Lew, DJ
Published Date
- November 3, 2014
Published In
Volume / Issue
- 24 / 21
Start / End Page
- R1050 - R1052
PubMed ID
- 25517371
Pubmed Central ID
- 25517371
Electronic International Standard Serial Number (EISSN)
- 1879-0445
Digital Object Identifier (DOI)
- 10.1016/j.cub.2014.09.042
Language
- eng
Conference Location
- England