Latent class analysis of discordance between results of drug use assessments in the CATIE data.
OBJECTIVE: The primary aim is to examine concordant/discordant results of drug use assessments in adults with schizophrenia. METHODS: Latent class analysis and multinomial logistic regression were used to examine concordance/discordance between drug use measures and identify characteristics differentiating participants across classes. RESULTS: Four classes - non-users, users, probable users, and RIA discordant - fit best. Age, sex, race/ethnicity, and psychiatric symptoms differed significantly across classes. CONCLUSIONS: Findings showed that discordance between results occurs at non-trivial rates and is, in part, attributable to individual characteristics. Results suggest the need for strategies to limit discordance and improve detection of drug use in adults with schizophrenia.
Johnson, KL; Desmarais, SL; Swartz, MS; Van Dorn, RA
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